SkinMedica

SkinMedica Retinol Complex 0.5 1 oz

SkinMedica sells retinol in three strengths, and 0.5 is the middle rung. That structure exists because retinol tolerance is built, not assumed. This is where most people land after acclimating at 0.25, and where many stay. Retinol works on cell turnover, so it addresses texture, uneven tone and fine lines together rather than one at a time. The trade-off is a break-in period: expect some dryness or flaking in the first weeks, which settles. Apply at night only, to dry skin, starting two or three evenings a week and building as tolerated. Follow with moisturizer. Daily sunscreen is mandatory, and retinol should be paused before and after resurfacing treatments.